{"id":840,"date":"2025-12-05T03:39:54","date_gmt":"2025-12-05T00:39:54","guid":{"rendered":"https:\/\/cell-bio.life\/?page_id=840"},"modified":"2026-02-10T10:50:32","modified_gmt":"2026-02-10T07:50:32","slug":"neural-crest-stem-cells","status":"publish","type":"page","link":"https:\/\/cell-bio.life\/de\/products\/stem-cells\/neural-crest-stem-cells\/","title":{"rendered":"Neuralleisten-Stammzellen"},"content":{"rendered":"

[vc_row wrap_container=\"yes\" content_placement=\"middle\" parallax=\"content-moving\" parallax_image=\"469\" parallax_speed_bg=\"1.4\" conditional_render=\"%5B%7B%22value_role%22%3A%22administrator%22%7D%5D\" css_params=\"\" el_class=\"ptopm pbotm form-block\" css=\".vc_custom_1765306545764{background-image: url(https:\/\/cell-bio.life\/wp-content\/uploads\/2025\/12\/back-1-scaled.webp?id=468) !important;background-position: center;background-repeat: no-repeat !important;background-size: cover !important;}\"][vc_column width=\"1\/5\"][\/vc_column][vc_column width=\"3\/5\"][vc_custom_heading text=\"Haben Sie Fragen zu unseren Produkten oder Dienstleistungen?\" font_container=\"tag:h2|text_align:center|color:%23ffffff\" use_theme_fonts=\"yes\" css_params=\"\"][vc_custom_heading text=\"Cell Bio entwickelt und optimiert L\u00f6sungen f\u00fcr jeden Kunden, um dessen Bed\u00fcrfnisse schnell und kosteneffizient zu erf\u00fcllen.\" font_container=\"tag:h4|text_align:center|color:%23ffffff\" use_theme_fonts=\"yes\" css_params=\"\"][vc_row_inner][vc_column_inner width=\"1\/2\"][vc_btn title=\"Anruf buchen\" style=\"outline\" shape=\"round\" color=\"blue\" size=\"xl\" align=\"right\" link=\"url:%23\" css_params=\"\" el_class=\"book-call-modal\"][\/vc_column_inner][vc_column_inner width=\"1\/2\"][vc_btn title=\"Bestellanfrage\" shape=\"round\" color=\"white\" size=\"xl\" align=\"left\" link=\"url:%2Fexpertise%2F\" css_params=\"\"][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column width=\"1\/5\"][\/vc_column][\/vc_row]<\/div>[\/vc_column][\/vc_row][vc_row full_width_css=“stretch_row_css“ wrap_container=“yes“ el_class=“banner-top ptopm pbotm“ css=“.vc_custom_1764896024504{background-image: url(https:\/\/cell-bio.life\/wp-content\/uploads\/2025\/12\/up-pic-Stem-cells-2-scaled.webp?id=679) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}“ conditional_render=“%5B%7B%22value_role%22%3A%22administrator%22%7D%5D“ css_params=““][vc_column width=“1\/3″][\/vc_column][vc_column width=“2\/3″][vc_custom_heading text=“Neuralleisten-Stammzellen“ font_container=“tag:h1|text_align:right“ use_theme_fonts=“yes“ css_params=““][vc_btn title=“Inventar ansehen“ shape=“round“ color=“white“ size=“xl“ align=“right“ link=“url:%2Fproducts%2Finventory%2F“ css_params=““][\/vc_column][\/vc_row][vc_row full_width_css=“stretch_row_css“ wrap_container=“yes“ el_class=“ptopm pbot“ conditional_render=“%5B%7B%22value_role%22%3A%22administrator%22%7D%5D“ css_params=““ css=“.vc_custom_1764894416498{background-image: url(https:\/\/cell-bio.life\/wp-content\/uploads\/2025\/12\/back-3-scaled.webp?id=470) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}“][vc_column][vc_row_inner el_class=“pbotm“ css_params=““][vc_column_inner][vc_column_text css=““ css_params=““]Neuralleistenstammzellen aus der Haut (NCSCs) sind multipotente Zellen, die in der Haut von Erwachsenen vorkommen und das Entwicklungspotenzial embryonaler Neuralleistenzellen beibehalten. Sie stellen eine leicht zug\u00e4ngliche, autologe Quelle f\u00fcr die regenerative Medizin und die Krankheitsmodellierung dar.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner]

[vc_toggle title=“Wichtigste Merkmale und Quellen“ css=““ css_params=““]Lokalisation:<\/strong>
\nDiese Zellen befinden sich vorwiegend in spezifischen Nischen:<\/p>\n
    \n
  • Haarfollikelwulst: Hier befinden sich epidermale neurale Stammzellen (EPI-NCSCs), die aus dem Ektoderm hervorgehen.<\/li>\n
  • Dermis: Enth\u00e4lt Hautvorl\u00e4uferzellen (SKPs), multipotente Zellen neuraler Abstammung.<\/li>\n
  • Interfollikul\u00e4re Epidermis: NCSCs k\u00f6nnen auch aus Keratinozytenkulturen neonataler und adulter Haut gewonnen werden.<\/li>\n<\/ul>\n

    Marker:<\/strong>
    \nDiese Zellen exprimieren typischerweise Marker wie p75NTR, SOX10, SOX2 und Nestin.<\/p>\n

    Expansion:<\/strong>
    \nSie werden h\u00e4ufig als Sph\u00e4roide (Hautsph\u00e4roide) in serumfreiem Medium mit EGF und FGF2 kultiviert.[\/vc_toggle][vc_toggle title=“Differenzierungspotenzial“ css=““ css_params=““]Hautstammzellen (NCSCs) k\u00f6nnen sich sowohl in vitro als auch in vivo in verschiedene Zelltypen differenzieren:<\/p>\n

      \n
    • Neuronale Zelllinien: Funktionelle sensorische Neuronen, Schwann-Zellen und Gliazellen.<\/li>\n
    • Pigmentzellen: Reife Melanozyten.<\/li>\n
    • Mesenchymale Zelllinien: Glatte Muskelzellen, Adipozyten (Fettzellen) und Chondrozyten (Knorpelzellen).<\/li>\n<\/ul>\n

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