Rheumatoid Arthritis (RA) is a chronic autoimmune disease where the immune system mistakenly attacks the body's own tissues, primarily the lining of the joints, causing painful swelling, stiffness, and potential joint damage, often affecting the hands and wrists symmetrically.
At Cell's Bio, we are helping our valued partner scientists to model and study disease behavior in order to find a cure, by explanting synoviocytes from a rheumatoid arthritis (RA) synovial membrane and culturing them to study the cells (fibroblast-like synoviocytes, or FLS) and their inflammatory secretions (cytokines, chemokines) in a 3D environment, maintaining cell-to-cell contact and tissue architecture.
This method allows researchers to model RA synovitis in vitro, analyze the pathogenic behavior of FLS (like aggressive proliferation and cytokine secretion), and test anti-inflammatory drugs, preserving the complex cellular interactions lost in traditional 2D cultures.
Email us at bd@cell-bio.life for more details.
Faithfully yours,
Cell Bio team





